They found that in vitro treatment of isolated peripheral blood neutrophils with simvastatin results in enhanced neutrophil velocity toward both IL-8 and fMLP (a potent polymorphonuclear leukocyte chemotactic factor) in COPD patients, restoring migratory accuracy to levels seen in control neutrophils from age-matched healthy donors (15). Here, CXCL8 is linked to chronic obstructive pulmonary disease.