It has been described, together with POSTN and chloride channel accessory 1, as a gene-signature for Th2 asthma and mainly IL-13 asthma phenotype (41), but until our knowledge, SERPINB2 protein expression has only been studied in broncoalveolar lavage (BAL) and never before at a peripheral level. The gene discussed is SERPINB2; the disease is asthma.