IFNG and neoplasm: We have recently shown that a decrease in cytotoxicity and lower IFN-γ secretion by osteoclast-expanded NK cells both from pancreatic cancer patients and tumor-bearing humanized BLT (hu-BLT) mice correlates with faster expansion of residual contaminating T cells within purified NK cells, whereas osteoclast-expanded NK cells from healthy human donors’ and hu-BLT mice with no tumors continue expanding super charged NK cells, while limiting T cell expansion for up to 30 to 60 days (51).