WNT1 and hepatocellular carcinoma: miR-122 expression level is found to be decreased significantly in human HCC tissue samples and cell lines, and overexpression of miR-122 inhibits proliferation but promotes hepatoma cell apoptosis by repressing Wnt1 expression, subsequently leads to blocking Wnt1/β-catenin/TCF signaling pathway (Xu J. et al., 2012; Ahsani et al., 2017) (Table 1).