ACKR3 and myocardial infarction: Of the few studies available, one study discovered that CXCL12-β protects cardiac cells via CXCR7 (Zhao et al., 2013) and evidence implied that CXCR7 signaling is able to take part in the regeneration process after myocardial infarction (Sierro et al., 2007; Yan et al., 2012).