SEMA5A expression (P = 0.032), tumor grade (P < 0.001), FIGO stage (P < 0.001), LMN (P < 0.001), presence of lymphatic invasion (P < 0.001), VEGF-C expression (P < 0.001), and LMVD (P = 0.005) remained independent prognostic factors for OS in the multivariate analysis. This evidence concerns the gene SEMA5A and neoplasm.