RN7SK and HIV-1 infection: The vast majority of genes identified to have a higher expression level in non-activated cells were non-coding small nuclear RNAs (snRNAs) with unknown relevance to HIV-1 infection, except for RN7SK, which forms an RNA scaffold that binds CDK9 and CycT1, thus sequestering these molecules from acting as a positive transcription elongation factor at the HIV-1 promoter36.