A recent study performed in interferon-alpha/beta receptor subunit 1 knock-out (Ifnar1-KO) mice, permissive to ZIKV replication, suggested that peripheral neurons and Schwann cells (SC) derived from dorsal root ganglia (DRG) explants are less susceptible to ZIKV infection as compared to CNS cells17. Here, IFNAR1 is linked to Zika virus infectious disease.