TGFB1 and Hepatic fibrosis: The activation and proliferation of hepatic stellate cells (HSCs) leads to the excess production and abnormal deposition of ECM components [3,4], as indicated in the cytological basis for liver fibrosis [5].Transforming growth factor β1 (TGFβ1) is closely related to liver fibrosis, and it is one of the most important fibrotic cytokines known so far [6].