MT-ATP8 and gout: When we categorized mutant alleles according to their positions in the mitochondrial genomes, 45 mutant alleles in patients with gout were located in the MT-ND5 region, followed-by the MT-CYB region (41 mutant alleles; 1 mutant allele was located in the overlapping MT-ATP6 and MT-ATP8 region) (Additional file 7).