Mucopolysaccharidosis (MPS) Type I (MPSI) can present as severe MPSI (Hurler syndrome) or attenuated MPSI (Hurler-Scheie, or Scheie syndrome), and is caused by mutations in the gene encoding the lysosomal enzyme α-L-iduronidase (IDUA) [1]. Here, IDUA is linked to mucopolysaccharidosis type 1.