In contrast to the tumor cells, the vast majority of adjacent mucosal cells lacks FUT8 staining, consistent with previous IHC studies for FUT8 in CRC [11, 15], although some normal mucosal cells in the basal layer tended to exhibit weak/equivocal staining (Fig 2A and 2B and S2 Fig). The gene discussed is FUT8; the disease is colorectal carcinoma.