The results showed that serum levels of TGF‐β, IL‐10 and sCTLA‐4 significantly reduced in vitiligo patients compared with healthy controls (TGF‐β: 5054.1 ± 1558.01 pg/mL vs 6929.7 ± 1298.47 pg/mL, P < .001; IL‐10: 8.39 ± 19.63 pg/mL vs 41.80 ± 60.15 pg/mL, P < .05; sCTLA‐4: 1017.9 ± 825.87 pg/mL vs 1846.8 ± 1223.91 pg/mL, P < .05) (Figure 3A‐C), which indicated that vitiligo Tregs have defects in secreting immunosuppressive cytokines. Here, IL10 is linked to vitiligo.