We also found that patients with a final diagnosis of EoE had significantly higher eos/hpf found on initial endoscopy compared to those with final diagnosis of PPI-REE (51.9 ± 30.6 vs. 35.8 ± 16.4, p = 0.027), as well as a higher likelihood of having IgE-mediated food allergy (79 vs. 47%, p = 0.003). Here, IGHE is linked to eosinophilic esophagitis.