In an in vitro study conducted on the fruit of A. muricata there was substantial repression of breast cancer cells growth (MDA-MB-468) as well as the selective suppression of the epidermal growth factor receptor (EGFR) (which regularly overexpressed in breast cancer) with IC50 of 4.8 μg/mL, while on non-tumorigenic human breast epithelial cells (MCF-10A) there was no effect (Dai et al., 2011). The gene discussed is EGFR; the disease is breast carcinoma.