SOX11 and neoplasm: SOX11’s potential regulation by a combinatorial PTM code may help to explain the observations that SOX11 upregulation can be associated with both, good or poor prognosis in different tumor types (Weigle et al., 2005; Wang et al., 2008; Brennan et al., 2009; Kuo et al., 2015) and that distinct retinal ganglion cell populations respond to SOX11 expression with opposing phenotypes, i.e., regeneration or cell death, in the lesion context (Norsworthy et al., 2017; Welsbie et al., 2017).