SOX11 and microcephaly: Mutations in SOX11 were found to be causal for Coffin-Siris Syndrome, a congenital disorder associated with intellectual disability and microcephaly, which illustrates the importance of SOX11 for human CNS development and underlines the need to understand SOX11’s regulation (Tsurusaki et al., 2014; Hempel et al., 2016).