INSR and progressive pseudorheumatoid arthropathy of childhood: To confirm the results of RNA-seq, real-time PCR was performed to detect the mRNA expression of DUSP1, INSR, RXRA, ADRB3, CNR1 and PPARG in PBMCs from control (n = 27), PPD patients with lower EPDS score (n = 28) and PPD patients with higher EPDS score (n = 28).