ITGAM and melanoma: In an antigen-specific T cell cytotoxicity assay in which the B16 melanoma tumor cell expressing hgp100 were co-cultured with splenocytes from Pmel-1 transgenic mice, Gr-1+CD11b+ cells from the spleen of miR-130a transgenic mice enhanced T cell cytotoxicity compared those from control mice (Fig. 4f; Supplementary Fig. 4c).