Among the differentially expressed miRNAs, miR-130a and miR-145 were down-regulated in Gr-1+CD11b+ myeloid cells from tumor-bearing mice and predicted to target the 3′-untranslated region (UTR) of TβRII mRNA (Fig. 1d; Supplementary Fig. 1a, and Supplementary Table 1). This evidence concerns the gene ITGAM and neoplasm.