In a time course experiment in which the Gr-1+CD11b+ cells were sorted from spleens of mice on day 7, 14, 21, or 28 after 4T1 tumor injection in the mammary fat pad (MFP), downregulation of miR-130 and miR-145 was inversely correlated with the increased levels of TβRII (Fig. 1g). The gene discussed is ITGAM; the disease is neoplasm.