Additionally, studies suggest that apo(a) isoform and Lp(a) concentration may have differential effects on coronary heart disease (CHD) odds14; however, distinguishing isoform-independent genetic effects on Lp(a) has required separate genotyping strategies, typically qPCR17, in addition to genotyping single-nucleotide polymorphisms (SNPs). This evidence concerns the gene AOPEP and coronary artery disorder.