Univariate analysis revealed significant correlations with AE for the following factors: gender, preoperative AE of IP, preoperative history of steroid use, preoperative CRP (C-reactive protein), LDH (lactate dehydrogenase), KL-6 (Krebs von den Lungen-6), %VC (vital capacity), FEV1.0 (forced expiratory volume in 1 s), FEV1.0%, DLCO (carbon monoxide diffusing capacity of the lung), operative time, blood loss, imaging findings of IP, and the surgical procedure used. The gene discussed is CRP; the disease is incontinentia pigmenti.