FOXN1 and hydrops fetalis: Prenatal stage:Foxn1 expression detected on E13 in the developing nasal region; and by E15.5–16.5 Foxn1 occupied entire epidermis including developing HF of the fur coat [19];2065 genes differentially regulated (up and down) between skin from B6 embryo at E14 (model of skin regeneration) and E18 (model of skin reparation) [41];Early neonatal stage:Foxn1 expression (postpartum days P1–P2) reported in the hair shaft and throughout the developing IRS and in a matrix compartment of hair bulb suggesting that Foxn1 correlates with the onset of terminal differentiation [19];