The enriched pathways for the downregulated genes included the JAK-STAT signalling pathway, natural killer cell-mediated cytotoxicity, MAPK signalling pathway, ErbB signalling pathway, pathways for several cancers, type II diabetes mellitus, Toll-like receptor signalling pathway, chemokine signalling pathway, GnRH signalling pathway, Fc gamma R-mediated phagocytosis, apoptosis, p53 signalling pathway, Wnt signalling pathway and insect hormone biosynthesis (figure 7c). This evidence concerns the gene TP53 and cancer.