Next, we extended our expression analyses of these 11 HSF1 targets to the cerebellum, and again found that the abundance of each transcript gene was significantly elevated in C9ORF72-ALS/FTLD relative to both controls and sporadic ALS cases (Additional file 8: Figure S3A, Additional file 7: Table S4). The gene discussed is HSF1; the disease is amyotrophic lateral sclerosis.