For example, perioperative levels of systemic proangiogenic cytokines such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and transforming growth factor beta (TGF-β) are increased in blood samples drawn from breast, lung, and gastric cancer patients during the perioperative period [33–35]. This evidence concerns the gene FGF2 and gastric cancer.