To determine the advantage of our PLS-based model in predicting response to TG tablets over various commonly used clinical and inflammatory parameters of RA, we compared its prediction efficacy with patients’ age, gender, erythrocyte sedimentation rate (ESR), as well as levels of C-reactive protein (CRP), rheumatoid factor (RF) and anti-cyclic citrullinated peptide (CCP) antibodies. Here, CRP is linked to rheumatoid arthritis.