SPARCL1 and gastrointestinal stromal tumor: According to the Fig. 5, the proliferation rates of the Lv-shSPARCL1, Lv-shNC and normal control group were similar in 24-, 48- and 72-h measurements (P > 0.05), which demonstrating that downregulation of SPARCL1 had no significant effect on GIST 882 cell growth in vitro.