We attempted to replicate the findings of Wirtwein et al. [12] on five CAD risk loci derived from large GWAS studies that were associated with non-dipping status and found that the A allele of rs9818870 in MRAS was significantly associated with reduced SBP and DBP dipping in our hypertensive patients with no evidence of CAD. This evidence concerns the gene MRAS and coronary artery disorder.