ACTA1 and Bloom syndrome: Our hypothesis was also supported by a previous study showing ASV could up‐regulate Smad7 in the TGF‐β1/Smad signaling pathway to inhibit the progress of EMT in peritoneal mesothelial cells.13 Importantly, Li et al17 identified that ASV inhibited the increased α‐SMA in the BLM‐induced fibrosis.