Inflammation and oxidative stress also play a pivotal role in pulmonary fibrosis.25 Studies supported that anti‐inflammation or antioxidant treatment strategies may achieved improvement in pulmonary fibrosis.26 We found the levels of inflammatory cytokine (TNF‐α and IL‐6) and markers of oxidative stress (MDA, SOD and GSH‐PX) in BLM‐treated rats were dramatically increased detected, whereas ASV prevented BLM‐induced elevation of inflammatory cytokine and oxidative stress. Here, SOD1 is linked to pulmonary fibrosis.