XIST and lung adenocarcinoma: LncRNAs have been verified to modulate the multiple resistance generation, involving cell cycle modulation, multidrug‐resistant protein and so on.25 For instance, lncRNA XIST is overexpressed in human lung adenocarcinoma A549 cells and increases the chemosensitivity to cisplatin, proposing the function through the let‐7i/BAG‐1 axis for the responsible for cisplatin resistance.26