VEGFA and cancer: Insulin‐like growth factor I (IGF‐I) is a peptide hormone that can induce mitosis, prevent apoptosis, promote angiogenesis through vascular endothelial growth factor (VEG‐F), and increase cell migration.5 Autocrine IGF‐I signalling from transformed cancerous cells is common, and is an implied mechanism for uncontrolled cell growth.6 A number of prospective studies have shown a consistent positive association between circulating IGF‐I concentration and risk of certain cancers such as colorectal, prostate and female breast7, 8, 9 cancer.