F3 and cancer: For instance, the capsular polysaccharides produced by Bacteroides fragilis ATCC25285 have been found to prevent intestinal inflammatory disease induced by pathogenic Helicobacter hepaticus (Mazmanian et al., 2008), and the tumor-specific Thomsen-Friedenreich antigen (TFα) secreted by B. ovatus D-6 with capsular polysaccharides is capable of sufficiently activating specific anti-TFα antibodies in vivo and thereby potentially prevent cancer development (Ulsemer et al., 2013).