CCL2 and inflammatory response: Thus, during animal model progress and modulation for not only panuveitis, but also for acute ocular inflammation (Rosenbaum et al., 1980), several chemokines and cytokines released by infiltrating cells, e.g., INFγ (interferon gamma), IL-1 (interleukin-1), TNFα (tumor necrosis factor alpha), IL-6 (interleukin-6), MCP-1 (monocyte chemoattractant protein-1), RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) and other inflammatory mediators, play an essential role (Trinh et al., 2008; Girol et al., 2013; Toguri et al., 2014).