Note that patients with pancreatic cancer produced significantly more IFNγ to PHA (p < 0.016) than HD while conversely, patients with pancreatic cancer exhibited significantly lower basal IFNγ production compared to patients with brain tumor as well as HD (p < 0.01, Additional file 1: Figure S1B).The basal IFNγ production was found to be higher in the patients with astrocytoma (A) as compared to HD and patients with pancreatic cancer (p < 0.001) as well with metastasis (p < 0.017). This evidence concerns the gene IFNG and brain neoplasm.