ESR1 and breast cancer: We found that (i) the expression (protein and mRNA) of FOXA1 and AR was closely related: the majority of cases expressing AR showed FOXA1 positivity, conversely, negative expression of FOXA1 correlates with very low level of AR; (ii) the expression of FOXA1 is strictly related to good outcome, and in the subgroup of patients with ER+ BC may provide more information on DFI than AR.