In addition, the mRNA and protein expression of IQUB in breast cancer cells MDA‐MB‐231 and MCF‐7 were significantly higher than that of normal breast cells MCF‐10A, while the expression of IQUB in the more aggressive MDA‐MB‐231 cells was even higher than that in the less aggressive MCF‐7 cells (P < .01) (Figure 1D). The gene discussed is IQUB; the disease is breast cancer.