KRT10 and Hyperkeratosis: Intradermal injection of this low dose of Treg prevented hyperkeratosis (Fig. 2A,E) (PBS 163.0 μm (36–212 μm), PBMC 301.3 μm (142–580 μm), PBMC + Treg 214.0 um (64–335.8 μm) (PBMC vs PBMC + Treg p = 0.0395), and prevented parakeratosis and acantosis, as well as the inflammation induced reduction of K10 expression (Fig. 2B,F) (PBS = 50.9% (24.6–67.2%), PBMC = 4.4% (0–27.3%), PBMC + Treg = 44.2% (5.6–65.2%) (PBMC vs PBMC + Treg p = 0.002)).