The greater expression levels of PPARδ target genes (Ucp2, Ucp3, Acox1, and Mcad) in the skeletal muscle of OO-GTE group, when compared to those of OO group, suggests that GTE enhances the transcription activity of PPARδ and induces fat metabolism in the skeletal muscle of OO-based HF diet-fed mice. This evidence concerns the gene UCP3 and hydrops fetalis.