MYC and neoplasm: This correlated significantly with massive induction of apoptosis and reduction of tumor cell proliferation in large areas of the tumors, which is typically observed after blocking MYC function in MYC ON/OFF and in the dominant negative Omomyc mouse tumor models63–66, as well as by 10008-F4 and by Mycro3 in neuroblastoma61 and pancreatic62 tumor models, respectively.