MYCN and neuroblastoma: As shown in Fig. 6D, MYCMI-6 (12.5 μM) dramatically increased cell death and reduced cell number in MYCN-amplified SK-N-DZ neuroblastoma cells after 24 hours treatment but had only marginal effects on the number of viable cells and the percentage of dead cells in normal lung (IMR-90) and foreskin (BJ) human fibroblasts.