MYC and neoplasm: The MYC-dependent effects of MYCMI-6 was further supported by the significant correlation between the levels of MYC mRNA/protein and the response to MYCMI-6 within the NCI-60 tumor cell line panel, and the differential response to MYCMI-6 between MYC knockout and wt/reconstituted Rat1 cells (Fig. 6 and Suppl.