In tumor tissue, lncRNA TUG1 is upregulated and promotes cell growth by increased transcription of the Bcl-2 gene and epigenetic silencing of cyclin-dependent protein kinase inhibitors (p15, p16, p21, p27, and p57) and proapoptotic genes (caspase-3, caspase-9, and Bax) (79–85). This evidence concerns the gene CDKN1A and neoplasm.