LncRNA UCA1 binds to several microRNAs in different tumors (e.g., miR-216b in liver cancer, miR-204 in esophageal and colon cancer, miR-27b in gastric cancer) and influences entire transcriptional programs as well as response toward therapy (90, 92, 312, 314, 315). This evidence concerns the gene UCA1 and colonic neoplasm.