The large repertoire of HAUSP viral substrates exemplify the role of HAUSP in various virus-associated cancers, such as Kaposi’s sarcoma,48 lymphomas,49 and nasopharyngeal cancer.50 These co-occurrences of HAUSP with viral proteins in the regulation of viral lytic and latency phases underscore its importance in host-virus interactions and immunity.51 This evidence concerns the gene USP7 and cancer.