Diminished killing of 2012-018 cells in stem cell medium may have been due to licensed KIR2DL2 and KIR2DL3 NK cells to cognate HLA-C*07:01 alleles that were also present in the GBM cells (Table 2; Figure 4A), thus calibrating these NK cells’ potency and explaining why there was no difference in responses of these cells to NK cell lysis between the two culture media (Table 2; Figure 4F). Here, HLA-C is linked to glioblastoma.