These authors showed that silencing NUP62 reduces the growth and viability of C4-2 cells, and provided evidence for the recruitment of NUP62, CaMKK2, and AR complexes to the AR-binding regions in the promoters of target genes such as PSA, suggesting a novel CaMKK2-NUP62 mechanism of AR transcriptional regulation in advanced PCa (107). This evidence concerns the gene AR and posterior cortical atrophy.