PTGS2 and major depressive disorder: The most common medications for mental disorders include medications for depression: selective serotonin reuptake inhibitors (SSRIs) and selective serotonin norepinephrine reuptake inhibitors (SSNRIs); anxiety: Benzodiazepines (e.g., Alprazolam and Clonazepam); pain: cyclooxygenase-2 (COX-2) inhibitors and opioids; attention: amphetamine, dextroamphetamine, and methylphenidate.