MTCH2 and Parkinson disease: Each miRNA interacted with several meta-DE genes, including miR-126-5p with MTCH2, VAVP, SNCA, and NDUFS1; miR-29a-3p with CDC42, TIMM8B, and SUB1; and miR-19b-3p with MAPK8, USP13, and KPNA6. Here, we outline the relationship analyzed above, including genes and pathways, particularly the main underlying pathway related to PD clustering by meta-DE genes (Figure 5B).