Among the 27 novel BCP ALL-associated genes identified, five have previously been implicated in other hematologic malignancies: DDX58 regulates proliferation of AML cells [11], ATXN1 and TAP2 polymorphisms are associated with increased risks of chronic lymphocytic leukemia and follicular lymphoma, respectively [12, 13], and deletion of Atg7 in a murine model results in a myeloproliferation resembling human AML [14]. The gene discussed is RIGI; the disease is acute myeloid leukemia.