TUG1 was highly expressed in diverse PCa cell lines, including LNCaP, DU145, PC3, and 22Rv1, as compared with that in an immortalized non-tumorigenic human prostate epithelial cell line RWPE1 cells, a finding confirmed by qRT-PCR assays (P<0.05; Figure 1D). Here, TUG1 is linked to posterior cortical atrophy.