GLIPR1 and neoplasm: The KD of Smed-Glipr1 resulted in the development of small epidermal blisters (white arrowheads in Fig. 4A) and tumor-like outgrowths (asterisks in Fig. 4A) in both unexposed and Cd-exposed regenerating animals, especially in head (n=15/24) and trunk (n=6/24) fragments.