Many MMPs are involved in tumor development, progression and metastasis (Merdad et al., 2014; Yamada et al., 2010); others, like MMP8 and MMP19, were found to limit tumorigenesis and/or metastasis (Impola et al., 2005; López-Otín et al., 2009). The gene discussed is MMP19; the disease is neoplasm.