We observed that 5% DSS feeding to wild-type (WT) mice resulted in a significant increase in the expression of MPR8 and F4/80 (also known as Adgre1) (Fig. 1A), markers commonly used to detect myeloid cells (Lagasse and Weissman, 1992; Mowat and Bain, 2011), indicating that myeloid cell infiltration is increased in DSS-induced colitis. This evidence concerns the gene ADGRE1 and colitis.