SOD2 and neoplasm: The recombinant oncolytic adenovirus ZD55-MnSOD (an antioxidant enzyme with tumour suppressor activity) enhances cisplatin-mediated growth suppression and apoptosis in OC cells, in vitro and in vivo, so the combination therapy of cisplatin and ZD55-MnSOD results in an improved survival rate, compared to monotherapy [112].