WFDC2 and neoplasm: Huang et al. demonstrated that IP administration of cationic biodegradable poly(β-amino ester) polymers may efficiently deliver diphtheria toxin subunit-A (DT-A) DNA to mice bearing ovarian tumours, using transcriptional regulation with the promoters of two genes, tumour-specific human epididymis protein 4 (HE4) and MSLN, whose activity is increased in OC cells [46].