lactobacilli mixture significantly affected the Wnt/β-catenin signaling by up-regulating AXIN2 gene (13.93-fold), a negative regulator of β-catenin, which plays a key role in human cancer as well as the cellular proliferation by increasing 10 times (Fc) the NF1 gene encoding for the neurofibromin protein, a tumour suppressor that prevent cells from uncontrolled proliferation. This evidence concerns the gene AXIN2 and cancer.